Women with a uterus will also use a progesterone gel or a placebo gel for the last 10 days of each month. If you are taking hormone replacement therapy to treat symptoms of menopause, your doctor will check every 3 to 6 months to see if you still need this medication. Author links open overlay panel Denise M. What special dietary instructions should I follow? Fulvestrant is used to treat metastatic breast cancer, most often after other hormone drugs like tamoxifen and often an aromatase inhibitor have stopped working. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only.